Where can I find a source for ReDox Signaling Molecules?


At the time of this publication, the only source of ReDox Signaling Molecules that I know of is through a company called ASEA.
I have set up a website so that you can easily get this information.
Here's the site: http://www.teamasea.com/richrotfort/
http://www.teamasea.com/richrotfort/


Monday, December 17, 2012

Clinical Study Changes in Athlete’s Redox State Induced by Habitual and Unaccustomed Exercise


Clinical Study:
Changes in Athlete’s Redox State Induced by Habitual and
Unaccustomed Exercise

This is an article that must be downloaded to view.

It is much more scientific than I wish to present on this blog.

If it is of interest to you...here's the link; http://scholar.google.com/scholar_url?hl=en&q=http://downloads.hindawi.com/journals/oximed/2012/805850.pdf&sa=X&scisig=AAGBfm1Y-Fik2ePD74wTGlSxxLl93mqFJQ&oi=scholaralrt






My source for Redox Signaling Molecules is through a company called ASEA. To use my source please click on this link: http://www.teamasea.com/richrotfort/

Research on Redox Signaling



According to a news article I just received....

The ARS Discoveries Journal 

will be publishing 36 articles on Redox Signaling in 2013.







Antioxidants & Redox Signaling (ARS) is the leading journal dedicated to the understanding of redox principles governing health and disease. This Journal provides and explores key aspects of the important and expanding world of redox-based therapeutics—genetic, pharmacological, and nutritional. Cutting-edge research focuses on structural biology, stem cells, regenerative medicine, epigenetics, imaging, clinical outcomes, and preventive and therapeutic nutrition, among other areas.

Here is the link to the home page of this journal: HERE





My source for Redox Signaling Molecules is through a company called ASEA. To use my source please click on this link: http://www.teamasea.com/richrotfort/

Sunday, December 2, 2012

Is Redox Signaling a Topic of Research?


Is Redox Signaling a Topic of Research?

I just did a Google Scholar Alert...Here's what came up:


Scholar Alert: [ redox signaling molecules ]


Physical activity and alpha-lipoic acid modulate inflammatory response through changes in thiol redox status

A Zembron-Lacny, M Gajewski, M Naczk, H Dziewiecka… - Journal of Physiology and …, 2012
... H2O2 is involved in regenerative processes through thiol redoxmodification of transcription factors
which induce the expression of many molecules such as cytokines and growth factors [8–10,
22]. The thiol redox status partic- ipates in cellular signalling pathways linking the ...

Impact of the redox-cycling herbicide diquat on transcript expression and antioxidant enzymatic activities of the freshwater snail< i> Lymnaea stagnalis</i>

A Bouétard, AL Besnard, D Vassaux, L Lagadic… - Aquatic Toxicology, 2012
... They also act as intracellular signalling molecules, under mechanisms that are not yet fully ... is
growing evidence that environmental toxicants able to induce alterations in redox homeostasis
and ... stress exert both agonistic and antagonistic effects on apoptoticsignaling ( [Curtin et ...

[PDF] Redox Regulation of Calcium Signaling in Cancer Cells by Ascorbic Acid Involving the Mitochondrial Electron Transport Chain

GG Martinovich, EN Golubeva, IV Martinovich… - Journal of Biophysics, 2012
... regulation, cell proliferation, apoptosis, hormonal signaling, and other fundamental cell functions
[3]. Organization and coordination of the redox activity of these elements occur through redox
circuits and depend on the intracellular concentration of redox-activemolecules [4, 5 ...

Vitamin C administration attenuates overload‐induced skeletal muscle hypertrophy in rats

Y Makanae, S Kawada, K Sasaki, K Nakazato, N Ishii - Acta Physiologica, 2012
... ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat
Rev Mol Cell Biol, 8, 813-824. Dickinson, BC, Peltier, J., Stone, D., Schaffer, DV, & Chang, CJ
2011. Nox2 redox signaling maintains essential cell populations in the brain. ...

[PDF] Compound stress response in stomatal closure: a mathematical model of ABA and ethylene interaction in guard cells

M Beguerisse-Díaz, MC Hernández-Gómez, AM Lizzul… - BMC Systems Biology, 2012
... in aperture are easy to observe and can be induced through changes in the concentration of
different signalling molecules... We now review briefly some of the relevant biology of the ABA
signalling network in guard cells, specifically in relation to redoxprocesses (see Figure 2 ...

… neuronal death: evidence for inhibition of ubiquitin-proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signalling

YW Yap, MJ Chen, ZF Peng, J Manikandan, JMJ Ng… - Neurochemistry …, 2012
... constituents were affected, such that eventual rupture of OMM would release mitochondrial
inter-space molecules, especially cytochrome ... dependent protein kinase II (CaMKII) inhibition
induces neurotoxicity via dysregulation of glutamate/calcium signalingand hyperexcitability. ...

Oxidative Stress Mediates Chemerin Induced Autophagy in Endothelial Cells

W Shen, C Tian, H Chen, Y Yang, D Zhu, P Gao, J Liu - Free Radical Biology and …, 2012
... The objective of this study is to investigate the molecular mechanisms of redox regulation of
autophagy in chemerin-induced angiogenesis in ... ROS function as keysignaling molecules that
regulate angiogenesis and are essential for endothelial cell proliferation and migration[59 ...

Redox Proteomics: Chemical Principles, Methodological Approaches and Biological/Biomedical Promises

A Bachi, I Dalle-Donne, A Scaloni - Chemical Reviews, 2012
... amounts of selected reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a
regulated way and through different mechanisms, also using some of them as signaling molecules
in many intra- or intercellular communication processes (redoxsignaling).(1) On the ...

Insulin signalling to the kidney in health and disease

LJ Hale, RJM Coward - Clinical Science, 2013
... There are also a number of critical nodes involved in insulinsignalling, including
the IR–IGF-IR complexes, IRS molecules and Akt/MAPK substrates that are able to
modify the biological effects of a ligand on a particular cell type. ...

Hormonal regulation of stem cell maintenance in roots

Y Lee, WS Lee, SH Kim - Journal of Experimental Botany, 2012
... Auxin binds to the auxin receptor known as TRANSPORT INHIBITOR RESPONSE
1/AUXIN-SIGNALING F-BOX PROTEINs (TIR1/AFBs), which is a ... It has been demonstrated that
the auxin-regulated redox status of the QC might be one of the factors involved in maintaining ...





My source for Redox Signaling Molecules is through a company called ASEA. To use my source please click on this link: http://www.teamasea.com/richrotfort/

Thursday, November 15, 2012

Plants Under Stress Use Redox Signaling

Plants Under Stress Use Redox Signaling


The impact of global change factors on redox signaling underpinning stress tolerance


Reduction/oxidation (redox) metabolism and associated signaling are key components of cross tolerance to biotic and abiotic stresses in plants.

For the full article: 
http://www.plantphysiol.org/content/early/2012/11/14/pp.112.205690.abstract

My source for Redox Signaling Molecules is through a company called ASEA. To use my source please click on this link: ASEA

Wednesday, November 14, 2012

Redox-signalling and antimicrobial peptides

Plants are permanently exposed to a great variety of microorganisms, such as viruses, mycoplasma, bacteria and fungi. However, similar to animals, plants possess an innate immune system. Redox molecules, such as nitric oxide or reactive oxygen species, and antimicrobial peptides, are important elements of this defense system to fight against pathogens and pests.



Here is the article in full: http://www.helmholtz-muenchen.de/biop/research-groups/redox-signalling-and-antimicrobial-peptides/index.html


My source for Redox Signaling Molecules is through a company called ASEA. To use my source please GO TO this link: http://www.teamasea.com/richrotfort/

Tuesday, November 13, 2012

Ageing...is it inevitable?

Ageing....is it inevitable?

Unfortunately yes it is....

But ageing Poorly is not.

Take a look at this short 2 minute video and make your own judgement.



Sunday, November 11, 2012

More Research from The German Cancer Research Center

German Cancer Research Center

Great article about Redox and Inflammation.....

Here's the Link >> Here<<

Looking for a Job as a REDOX SIGNALING Researcher?


PhD Position in Cancer Biology : Heidelberg, Germany




Open PhD position
Our laboratory at the German Cancer Research Center (DKFZ) in Heidelberg, Germany,
is interested in the role of redox signaling and protein redox regulation in tumor cells
(for more information seehttp://www.dkfz.de/en/redoxregulation/).
The PhD position will be part of the newly established Collaborative Research Center (Sonderforschungsbereich, SFB) “Cellular surveillance and damage
 response” (see http://www.zmbh.uni-heidelberg.de/sfb1036/).
The project ‘Thiol peroxidases as sensors and transmitters of cytoprotective peroxide signals’ will address the role of thiol peroxidases in transcription factor regulation. We employ a broad range of techniques, ranging from Molecular Biology and Biochemistry (redox-dependent protein-protein interactions) to Cell Biology (live-cell imaging) and in vivo studies (transgenic mice).
We are an English-speaking, international laboratory with a friendly and productive work atmosphere and state-of-the-art equipment, located in Germany’s largest biomedical research institute. Successful candidates will enter the Helmholtz International Graduate School for Cancer Research.
Applicants must have a Master degree or equivalent in Biology, Biochemistry or related fields. Candidates should have a strong background in Biochemistry, Molecular Biology and/or Cell Biology. We expect excellent communication skills in English and enthusiasm for science.
Applications must include a cover letter, CV, copies of high school and university exams, and two letters of reference. Please send your application as one pdf file to t.dick@dkfz.de.
Source: http://www.nature.com/naturejobs/science/jobs/292293-PhD-Position-in-Cancer-Biology

Saturday, November 10, 2012

Even Plants Use Signaling Molecules---


Yes, Even Plants Use Signaling Molecules---




Signaling mechanisms integrating carbon and nitrogen utilization in plants



Abstract

Carbon (C) and nitrogen (N) are two essential nutrients affecting plant growth and development. Plants are non-motile organisms and have evolved highly sophisticated and complex sensing and signaling mechanisms to respond to the dynamic changes of C and N nutrients in their surroundings. C and N metabolism are tightly coordinated to maintain intracellular C/N homeostasis. However, the regulatory mechanism underlying C/N coordination and balancing in plants remains to be elucidated. It has been suggested that C and N metabolism are modulated by the interaction of C signaling with N signaling or by C/N ratio signaling. This review focuses on cell signaling studies that provide insight into the regulation mechanism of C/N balancing in plants.

 Source: http://www.springerlink.com/content/1570867w1726n387/



WHERE CAN I FIND A SOURCE FOR REDOX SIGNALING MOLECULES?

At the time of this publication, the only source of ReDox Signaling Molecules that I know of is through a company called ASEA.

I have set up a website so that you can easily get this information.

Here's the site: www.ASEAofSuccess.com

ASEA, Redox signaling molecules and Metabolites


ASEA, Redox signaling molecules and Metabolites



More and more research is showing up about Redox Signaling Molecules




WHERE CAN I FIND A SOURCE FOR REDOX SIGNALING MOLECULES?

At the time of this publication, the only source of ReDox Signaling Molecules that I know of is through a company called ASEA.

I have set up a website so that you can easily get this information.

Here's the site:  www.ASEAofSuccess.com


Friday, November 9, 2012

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

An emerging aspect of redox signaling is the pathway mediated by electrophilic byproducts, such as nitrated cyclic nucleotide (for example, 8-nitroguanosine 3′,5′-cyclic monophosphate (8-nitro-cGMP)) and nitro or keto derivatives of unsaturated fatty acids, generated via reactions of inflammation-related enzymes, reactive oxygen species, nitric oxide and secondary products.


Redox Signaling in Adult Stem Cell Biology


Indeed, consolidated evidences highlight the importance of redox signalling in the homeostasis of fundamental processes in cell adaptive biology and particularly in controlling the balance between self-renewal and differentiation of stem cells.



In the presented study we investigated the effect of DFX and DFO on the redox homeostasis of hematopoietic stem/progenitor cells (HSPCs) in order to get insights on the differential effect of iron chelators in rescuing altered hematopoiesis.

Redox signaling, mediated by ROS production and likely triggered by changes in the environmental oxygen tension, appears to be essential in regulating HSC self-renewal and preservation of pluripotency

Source of this article

Friday, October 19, 2012



R. Andrew Shanely1, David C. Nieman1, Dru A. Henson1, Amy M. Knab1, Lynn Cialdella-Kam1, Mary Pat Meaney1, Sara Baxter2 and Wei Sha3
1 Human Performance Laboratory, Appalachian State University, UNC-Charlotte, North Carolina Research Campus, Kannapolis, NC
2 Analytical Sciences, David H. Murdock Research Institute, UNC-Charlotte, North Carolina Research Campus, Kannapolis, NC
3 Bioinformatics Services Division, UNC-Charlotte, North Carolina Research Campus, Kannapolis, NC
We determined if drinking ASEA™, a redox-signaling molecule beverage, would 
  • improve cycling performance
  • counter inflammation, oxidative stress, and immune dysfunction, 
  • and alter the metabolite profile. 
The full article can be accessed at: http://www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/lb713?sid=c4261da1-f8d2-4932-94a0-ca395b0d1d8e

Thursday, October 18, 2012

American Health Journal - Report on Asea Dr Ward, Dr Samuleson - Redox S...

Redox- and Expression- Proteomic analysis of Plasma biomarkers in Bladder Transitional Cell Carcinoma - Molecular BioSystems (RSC Publishing)

Redox- and Expression- Proteomic analysis of Plasma biomarkers in Bladder Transitional Cell Carcinoma - Molecular BioSystems (RSC Publishing)

Professional News: October 17, 2012




Awards and Honors


Kheng Newick and Brian Cunniff, two University of Vermont doctoral students in the Cell, Molecular and Biomedical Sciences Program, recently received prestigious awards.

 Newick received a travel award to attend the International Mesothelioma Interest Group (iMIG) meeting, which took place September 11 to 14, 2012 in Boston, Mass., where she presented a poster titled 
“Combinatorial Approaches for Targeting Mitochondrial Redox Signaling and FOXM1 Expression in Malignant Mesothelioma.” 

Cunniff was recently awarded a four-month Society for Free Radical Biology and Medicine Research mini-fellowship, which began in September 2012. Currently working in Cambridge, England with Michael Murphy, Ph.D., in the Mitochondrial Biology Unit of the Medical Research Council, Cunniff is conducting a research project titled
“Combinatorial Approaches for Targeting Mitochondrial Redox Signalling and FOXM1 Expression in Malignant Mesothelioma.”

 He was also recently presented a Young Investigator Award for his platform presentation titled “Mitochondrial Architecture, Oxidant Production and Redox Signaling in Malignant Mesothelioma Cells,” at the Society for Free Radical Research International meeting, which was held September 6 to 9, 2012, at Imperial College in London, England. Both students are being mentored by Nicholas Heintz, professor of pathology. Learn more.


Professional News: October 17, 2012

Information about Redox Signaling Molecules

I'll search the literature to bring you current information on Redox Signaling Molecules